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American Society of Microbiology ABMM Sample Questions (Q198-Q203):
NEW QUESTION # 198
A patient returning from a hiking trip in a Lyme disease-endemic area presents with a unilateral facial nerve palsy, headache, and neck stiffness. Serological testing for Borrelia burgdorferi by ELISA is positive, but a Western blot shows only IgM bands. The MOST appropriate interpretation of these results is:
- A. The patient has chronic Lyme disease with a persistent IgM response.
- B. The patient has a co-infection with another tick-borne pathogen causing a non-specific IgM response.
- C. The patient has early Lyme disease, and the IgM response is characteristic of recent infection.
- D. The patient has a false-positive ELISA result, and Lyme disease is unlikely.
Answer: C
NEW QUESTION # 199
A patient develops a severe diarrheal illness after consuming raw oysters. Stool cultures grow a Gram- negative, comma-shaped bacterium that is oxidase-positive and grows on thiosulfate-citrate-bile salts-sucrose (TCBS) agar, producing green colonies. The MOST likely virulence factor contributing to the watery diarrhea is:
- A. Cholera toxin-like enterotoxin
- B. Shiga toxin
- C. Heat-labile toxin (LT)
- D. Cytotoxin-associated gene A (CagA)
Answer: A
NEW QUESTION # 200
A patient develops a severe diarrheal illness after returning from a backpacking trip where they drank untreated stream water. Stool examination reveals motile trophozoites with multiple flagella and a prominent ventral sucking disk. The MOST likely causative agent is:
- A. Cyclospora cayetanensis
- B. Entamoeba histolytica
- C. Cryptosporidium parvum
- D. Giardia lamblia
Answer: D
NEW QUESTION # 201
A patient with a history of intravenous drug use develops a bloodstream infection with Staphylococcus aureus. Antimicrobial susceptibility testing reveals resistance to methicillin. The mechanism of methicillin resistance in Staphylococcus aureus is primarily mediated by:
- A. Increased expression of efflux pumps.
- B. Alteration of penicillin-binding proteins (PBPs).
- C. Acquisition of genes encoding aminoglycoside-modifying enzymes.
- D. Production of beta-lactamase enzymes.
Answer: B
NEW QUESTION # 202
A patient with severe combined immunodeficiency (SCID) develops a progressive respiratory illness.
Bronchoalveolar lavage fluid is examined using direct fluorescent antibody (DFA) staining, which reveals numerous cysts of Pneumocystis jirovecii. The cysts appear:
- A. Large and multinucleated with prominent endospores.
- B. Cup-shaped or helmet-shaped with internal structures.
- C. Oval-shaped with a thin wall and internal nuclei.
- D. Small and round with a thick wall, containing sporozoites.
Answer: B
NEW QUESTION # 203
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